Dr Gillian Dite

Publications

2017

Dite GS, MacInnis R, Bickerstaffe A, Dowty JG, Milne RL, Antoniou AC, et al. Testing for gene–environment interactions using a prospective family cohort: body mass index in early and later adulthood and risk of breast cancer. American Journal of Epidemiology 2017; 185: 487–500.

Nguyen TL, Aung YK, Evans CF, Dite GS, et al. Mammographic density defined by higher than conventional brightness thresholds better predicts breast cancer risk. International Journal of Epidemiology 2017; 46: 652–661.

Machalek DA, Wark JD, Tabrizi SN, Hopper JL, Bui M, Dite GS, et al (2016). Genetic and environmental factors in invasive cervical cancer: design and methods of a classical twin study. Twin Research and Human Genetics 2017; 20: 1–9.

Hopper JL, Dite GS, Byrnes GB. Risks to relatives. In Encyclopedia of Life Sciences 2017. Chichester, United Kingdom: John Wiley & Sons, pp. 1–6.

Nguyen TL, Choi Y-H, Aung YK, Evans CF, Trinh NH, Li S, Dite GS, et al. Breast cancer risk associations with digital mammographic density by pixel brightness and mammographic system. Radiology in press.

Li S, Wong EM, Nguyen TL, Joo J-HE, Stone J, Dite GS, et al. (2017) Causes of blood methylomic variation for middle-aged women measured by the HumanMethylation450 array. Epidgenetics in press.

2016

Dite GS, Macinnis RJ, Bickerstaffe A, Dowty JG, Allman R, Apicella C, et al. Breast cancer risk prediction using clinical models and 77 independent risk-associated SNPs for women aged under 50 years: Australian Breast Cancer Family Registry. Cancer Epidemiology, Biomarkers and Prevention 2015; 25: 359–365.

Ballinger ML, Goode DL, Ray-Coquard I, James PA, Mitchell G, Niedermayr, E., … , Dite GS, et al. International Sarcoma Kindred Study. Monogenic and polygenic determinants of sarcoma risk: an international genetic study. Lancet Oncology 2016; 17: 1261–1271.

Jenkins MA, Makalic E, Dowty JG, Schmidt DF, Dite GS, et al. Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening. Future Oncology 2016; 12: 503–513.

Hopper JL, Nguyen TL, Stone J, Aujard K, Matheson MC, Abramson MJ, … , Dite GS, et al. Childhood body mass index and adult mammographic density measures that predict breast cancer risk. Breast Cancer Research and Treatment 2016; 156: 163–170.

2015

Allman R, Dite GS, Hopper JL, Gordon O, Starlard-Davenport A, Chlebowski R, Kooperberg C. SNPs and breast cancer risk prediction for African American and Hispanic women. Breast Cancer Research and Treatment 2015; 154: 586–589.

Win AK, Buchanan DD, Rosty C, Macinnis RJ, Dowty JG, Dite GS, et al. Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives. Gut 2015; 64: 101–110.

Li S, Wong EM, Joo JE, Jung C-L, Chung J, Apicella C, … , Dite GS, et al. Genetic and environmental causes of variation in the difference between biological age based on DNA methylation and chronological age for middle-aged women. Twin Research and Human Genetics 2015; 18: 720–726.

2014

Heath JA, Smibert E, Algar AM, Dite GS, Hopper JL. Cancer Risks for Relatives of Children with Cancer. Journal of Cancer Epidemiology 2014; 2014: 806076.

Work ME, John EM, Andrulis IL, Knight JA, Liao Y, Mulligan AM, … , Dite GS, et al. Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry. British Journal of Cancer 2014; 110: 1367–1377.

Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, … , Dite GS, et al. A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the Breast Cancer Association Consortium. Human Molecular Genetics 2014; 23: 1934–1946.

Johnson N, Dudbridge F, Orr N, Gibson L, Jones ME, Schoemaker MJ, … , Dite GS, et al. Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. Breast Cancer Research 2014; 16: R51.

Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, … , Dite GS, et al. 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy. Nature Communications 2014; 5: 4051.

Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, … , Dite GS, et al. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. Human Molecular Genetics 2014; 23: 6034–6046.

2013

Dite GS, Mahmoodi M, Bickerstaffe A, Hammett F, Macinnis RJ, Tsimiklis H, et al. Using SNP genotypes to improve the discrimination of a simple breast cancer risk prediction model. Breast Cancer Research and Treatment 2013; 139: 887–896.

Nguyen TL, Schmidt DF, Makalic E, Dite GS, Stone J, Apicella C, et al. Explaining variance in the cumulus mammographic measures that predict breast cancer risk: a twins and sisters study. Cancer Epidemiology, Biomarkers and Prevention 2013; 22: 2395–2403.

MacInnis RJ, Bickerstaffe A, Apicella C, Dite GS, Dowty JG, Aujard K, et al. Prospective validation of the breast cancer risk prediction model BOADICEA and a batch-mode version BOADICEACentre. British Journal of Cancer 2013; 109: 1296–1301.

Teo ZL, Provenzano E, Dite GS, Park DJ, Apicella C, Sawyer SD, et al. Breast tumour morphology predicts PALB2 germline mutation status. British Journal of Cancer 2013; 109: 154–163.

Bui M, Bjørnerem Å, Ghasem-Zadeh A, Dite GS, Hopper JL and Seeman E. Architecture of cortical bone determines in part its remodelling and structural decay. Bone 2013; 55: 353–358.

Michailidou K, Hall P, Gonzalez-Neira A, Ghoussanini M, Dennis J, Milne RL, … , Dite GS, et al. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nature Genetics 2013; 45: 353–361.

2012

Dite GS, Makalic E, Schmidt DF, Giles GG, Hopper JL and Southey MC. Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry. Breast Cancer Research 2012; 14: R122.

Dite GS, Stone J, Chiarelli AM, Giles GG, English DR, Cawson JC and Hopper JL. Are genetic and environmental components of variance in mammographic density measures that predict breast cancer risk independent of within-twin pair differences in body mass index? Breast Cancer Research and Treatment 2012; 131: 553–559.

Stone J, Dite GS, Giles GG, Cawson J, English DR and Hopper JL. Inference about causation from elimination of familial confounding: application to longitudinal twin data on mammographic density measures that predict breast cancer risk. Cancer Epidemiology, Biomarkers and Prevention 2012; 21: 1149–1155.

Downing ME, Dite GS, Ballinger ML and The International Sarcoma Kindred Study Consortium. An increased incidence of Hodgkin’s lymphoma in patients with adult-onset sarcoma. Clinical Sarcoma Research 2012; 2: 1.

Hopper JL, Jenkins MA, Dowty JG, Dite GS, Apicella C, Keogh L, et al. Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers. Pathology 2012; 44: 89–98.

Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, et al. 11q13 is a susceptibility locus for hormone receptor positive breast cancer. Human Mutation 2012; 33: 1123–1132.

2011

Milne RL, John EM, Knight JA, Dite GS, Southey MC, Giles GG, et al. The potential value of sibling controls compared with population controls for association studies of lifestyle-related risk factors: an example from the Breast Cancer Family Registry. International Journal of Epidemiology 2011; 40: 1342–1354.

Southey MC, Ramus SJ, Dowty JG, Smith LD, Tesoriero AA, Wong EE, Dite GS, et al. Morphological predictors of BRCA1 germline mutations in young women with breast cancer. British Journal of Cancer 2011; 104: 903–909

Kurian AW, Gong GD, John EM, Johnston DA, Felberg A, West DW, … , Dite GS, et al. Breast Cancer Risk for Non-Carriers of Family-Specific BRCA1 and BRCA2 Mutations: Findings from the Breast Cancer Family Registry. Journal of Clinical Oncology 2011; 29: 4505–4509.

Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, et al. Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Human Molecular Genetics 2011; 20: 3289–3303.

Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, … , Dite GS, et al. Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer. Cancer Epidemiology, Biomarkers and Prevention 2011; 20: 2222–2231.

Stevens KN, Garcia-Closas M, Fredericksen Z, Kosel M, Pankratz VS, Hopper JL, Dite GS, et al. Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk. British Journal of Cancer 2011; 105: 1934–1939.

Yang XR, Chang-Claude J, Goode EL, Couch FJ, Nevanlinna H, Milne RL, … , Dite GS, et al. Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. Journal of the National Cancer Institute 2011; 103: 250–263.

2010

Dite GS, Whittemore AS, Knight JA, John EM, Milne RL, Andrulis IL, et al. Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations. British Journal of Cancer 2010; 103: 1103–1108.

Odefrey F, Stone J, Gurrin LC, Byrnes GB, Apicella C, Dite GS, et al. Common genetic variants associated with breast cancer and mammographic density measures That Predict Disease. Cancer Research 2010; 70: 1449–1458.

Turkovic L, Gurrin LC, Bahlo M, Dite GS, Southey MC and Hopper JL. Comparing the frequency of common genetic variants and haplotypes between carriers and non-carriers of BRCA1 and BRCA2 deleterious mutations in Australian women diagnosed with breast cancer before 40 years of age. BMC Cancer 2010; 10: 466.

Fehringer G, Ozcelik H, Knight JA, Paterson AD, Dite GS, Giles GG, et al. Family-based association study of IGF1 microsatellites and height, weight, and body mass index. Journal Of Human Genetics 2010; 55: 255–258.

Milne RL, Gaudet MM, Spurdle AB, Fasching PA, Couch FJ, Benítez J, … , Dite GS, et al. Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk. Breast Cancer Research 2010; 12: R110.

2009

Fehringer G, Boyd NF, Knight JA, Paterson AD, Dite GS, Giles GG, et al. Family-based genetic association study of insulin-like growth factor I microsatellite markers and premenopausal breast cancer risk. Breast Cancer Research and Treatment 2009; 118: 415–424.

Milne RL, Benitez J, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, … , Dite G, et al. Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. Journal of the National Cancer Institute 2009; 101: 1012–1018.

2008

Dite GS, Gurrin LC, Stone J, Gunasekara A, McCredie MRE, English DR, et al. Predictors of mammographic density: insights gained from novel regression analysis of a twin study. Cancer Epidemiology, Biomarkers and Prevention 2008; 17: 3474–3481.

Phillips K-A, Osborne RH, Giles GG, Dite GS, Apicella C, Hopper JL and Milne RL. Psychosocial factors and survival of young women with breast cancer: a population-based prospective cohort study. Journal of Clinical Oncology 2008; 26: 4666–4671.

Hammet F, George J, Tesoriero AA, Jenkins MA, Schroen C, Smith L, Grabosch-Meehan A, Dite G, et al. Is BRCA2 c.9079 G>A a predisposing variant for early onset breast cancer? Breast Cancer Research and Treatment 2008; 109: 177–179.

Dowty JG, Lose F, Jenkins MA, Chang JH, Chen X, Beesley J, Dite GS, et al. The RAD51D E233G variant and breast cancer risk: population-based and clinic-based family studies of Australian women. Breast Cancer Research and Treatment 2008; 112: 35–39

Hopper J, Dite G and Byrnes G. Risks to relatives. In Encyclopedia of Life Sciences 2008. Chichester, United Kingdom: John Wiley & Sons, pp. 1–6.

2007

Balise RR, Chen Y, Dite G, Felberg A, Sun L, Ziogas A and Whittemore AS. Imputation of missing ages in pedigree data. Human Heredity 2007; 63: 168–174.

Smith LD, Tesoriero AA, Ramus SJ, Dite G, Royce SG, Giles GG, et al. BRCA1 promoter deletions in young women with breast cancer and a strong family history: a population-based study. European Journal of Cancer 2007; 43: 823–827.

John EM, Phipps AI, Knight JA, Milne RL, Dite GS, Hopper JL, et al. Medical radiation exposure and breast cancer risk: findings from the Breast Cancer Family Registry. International Journal of Cancer 2007; 121: 386–394.

Stone J, Gurrin LC, Byrnes GB, Schroen CJ, Treloar SA, Padilla EJ, Dite GS, et al. Mammographic density and candidate gene variants: a twins and sisters study. Cancer Epidemiology, Biomarkers and Prevention 2007; 16: 1479–1484.

Spurdle AB, Chang JH, Byrnes GB, Chen X, Dite GS, McCredie MR, et al. A systematic approach to analysing gene-gene interactions: polymorphisms at the microsomal epoxide hydrolase EPHX and glutathione S-transferase GSTM1, GSTT1, and GSTP1 loci and breast cancer risk. Cancer Epidemiology, Biomarkers and Prevention 2007; 1: 769–774.

Apicella C, Dowty JG, Dite GS, Jenkins MA, Senie RT, Daly MB, et al. Validation study of the LAMBDA model for predicting the BRCA1 or BRCA2 mutation carrier status of North American Ashkenazi Jewish women. Clinical Genetics 2007; 72: 87–97.

2006

Stone J, Dite GS, Gunasekara A, English DR, McCredie MR, Giles GG, et al. The heritability of mammographically dense and nondense breast tissue. Cancer Epidemiology, Biomarkers and Prevention 2006; 15: 612–617.

Knight JA, John EM, Milne RL, Dite GS, Balbuena R, Shi EJQ, et al. An inverse association between ovarian cysts and breast cancer. International Journal of Cancer 2006; 118: 197–202.

Gurrin LC, Carlin JB, Sterne JAC, Dite GS and Hopper JL. Using bivariate models to understand between- and within-cluster regression coefficients with application to twin data. Biometrics 2006; 62: 745–751.

Wharton CL, Dharmage SC, Jenkins MA, Dite GS, Giles GG, Abramson MJ, et al. Tracing 8,600 participants 36 years after recruitment at age 7 for the Tasmanian Asthma Study. Australian and New Zealand Journal of Public Health 2006; 30: 105–110.

Dite GS, Wark JD, Giles, GG, English DR, McCredie MRE and Hopper JL. Is there a positive association between mammographic density and bone mineral density? (letter) Breast Cancer Research 2006; 8: 401.

2005

Dite GS, Wark JD, Giles, GG, English DR, McCredie MRE and Hopper JL. Is there overlap between the genetic determinants of mammographic density and bone mineral density? Cancer Epidemiology, Biomarkers and Prevention 2005; 14: 2266–2268.

Milne RL, Knight JA, John EM, Dite GS, Balbuena R, Ziogas A, et al. Oral contraceptive use and risk of early-onset breast cancer in carriers and non-carriers of BRCA1 and BRCA2 mutations. Cancer Epidemiology, Biomarkers and Prevention 2005; 14: 350–356.

Chang J-H, Gertig DM, Chen X, Dite GS, Jenkins MA, Milne RM, et al. CYP17 genetic polymorphism, breast cancer, and breast cancer risk factors: Australian Breast Cancer Family Registry. Breast Cancer Research 2005; 7: R513–R521.

Spurdle AB, Antoniou AC, Duffy DL, Pandeya N, Kelemen L, Chen X, … , Dite GS, et al. The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research 2005; 7: R176–R183.

Montgomery KG, Gertig DM, Chen X, Dite GS, McCredie MR, Giles GG, et al. The AIB1 glutamine repeat polymorphism is not associated with the risk of breast cancer before age 40 years in Australian women. Breast Cancer Research 2005; 7: R353–R356.

Hopper JL, Hayes VM, Spurdle AM, Chenevix-Trench G, Jenkins MA, Milne RL, Dite GS, et al. A protein truncating mutation in CYP17A1 in three sisters with early-onset breast cancer. Human Mutation 2005; 26: 298–302.

2004

Richardson A, Cox B, McCredie M, Dite G, Chang J-H, Gertig D, et al. Cytomegalovirus, Epstein-Barr virus and risk of breast cancer before age 40 years: a case-control study. British Journal of Cancer 2004; 90: 2149–2152.

2003

Dite GS, Jenkins MA, Southey MC, Hocking JS, Giles GG, McCredie MRE, et al. Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutations. Journal of the National Cancer Institute 2003; 95: 448–557.

McCredie MRE, Dite GS, Southey MC, Venter DJ, Giles GG and Hopper JL. Risk factors for early-onset breast cancer by estrogen receptor and progesterone receptor status. British Journal of Cancer 2003; 89: 1661–1663.

Cui J, Spurdle AB, Southey MC, Dite GS, Venter DJ, McCredie MRE, et al. Regressive logistic and proportional hazards disease models for within-family analyses of measured genotypes, with application to a CYP17 polymorphism and breast cancer. Genetic Epidemiology 2003; 24: 161–172.

Montgomery KG, Gertig DM, Baxter SW, Milne RL, Dite GS, McCredie MR, et al. The HER2 I655V polymorphism and risk of breast cancer in women < age 40 years. Cancer Epidemiology, Biomarkers and Prevention 2003; 10: 1109–1111.

2002

Boyd NF, Dite GS, Stone J, Gunasekara A, English DR, McCredie MRE, et al. Heritability of mammographic density, a risk factor for breast cancer. New England Journal of Medicine 2002; 347: 886–894.

Jenkins MA, Baglietto L, Dite GS, Jolley DJ, St. John DJB, Macrae FA, et al. After hMSH2 and hMLH1-what next? Analysis of three-generational, population-based, early–onset colorectal cancer families. International Journal of Cancer 2002; 102: 166–171.

Spurdle AB, Hopper JL, Chen X, Dite GS, Cui J, McCredie MR, et al. The BRCA2 372 HH genotype is associated with risk of breast cancer in Australian women under age 60 years. Cancer Epidemiology, Biomarkers and Prevention 2002; 11: 413–416.

Hopper JL and Dite GS. Presenting statistical uncertainty in trends and dose-response relationships. (letter) American Journal of Epidemiology 2002; 155: 977–978.

2001

McCredie MRE, Dite GS, Porter L, Maskiell J, Giles GG, Phillips K-A, et al. Prevalence of self-reported arm morbidity following treatment for breast cancer in the Australian Breast Cancer Family Study. The Breast 2001; 10: 515–522.

Cui JS, Antoniou AC, Dite GS, Southey MC, Venter DJ, Easton DF, et al. After BRCA1 and BRCA2 – what next? Multifactorial segregation analyses of three-generational, population-based Australian female breast cancer families. American Journal of Human Genetics 2001; 68: 420–431.

Spurdle AB, Hopper JL, Chen X, Dite GS, McCredie MRE, Giles GG, et al. The steroid 5alpha-reductase type II TA repeat polymorphism is not associated with risk of breast cancer or ovarian cancer in Australian women. Cancer Epidemiology, Biomarkers and Prevention 2001; 10: 1287–1293.

2000

Spurdle AB, Hopper JL, Dite GS, Chen X, Cui J, McCredie MRE, et al. CYP17 promoter polymorphism and breast cancer in Australian women under age forty years. Journal of the National Cancer Institute 2000; 92: 1674–1681.

1999

Southey MC, Tesoriero AA, Andersen CR, Jennings KM, Brown SM, Dite GS, et al. BRCA1 mutations and other sequence variants in a population-based sample of Australian women with breast cancer. British Journal of Cancer 1999; 79: 34–39.

Spurdle AB, Dite GS, Chen X, Mayne CJ, Southey MC, Batten LE, et al. Androgen receptor exon 1 CAG repeat length is not a risk factor for breast cancer in women under before age forty years. Journal of the National Cancer Institute 1999; 91: 961–966.

Hopper JL, Southey MC, Dite GS, Jolley DJ, Giles GG, McCredie MRE, et al. Population-based estimate of the average age-specific cumulative risk of breast cancer for a defined set of protein truncating mutations in BRCA1 and BRCA2. Cancer Epidemiology, Biomarkers and Prevention 1999; 8: 741–747.

Firgaira FA, Seshadri R, McEvoy CRE, Dite GS, Giles GG, McCredie MRE, et al. HRAS1 rare minisatellite alleles and breast cancer in Australian women under age forty. Journal of the National Cancer Institute 1999; 91: 2107–2111.

Hopper JL, Chenevix-Trench G, Jolley DJ, Dite GS, Jenkins MA, Venter DJ, et al. Design and analysis issues in a population-based case-control-family study of the genetic epidemiology of breast cancer, and the Cooperative Family Registry for Breast Cancer Studies (CFRBCS). Journal of the National Cancer Institute Monographs 1999; 26: 95–100.

Armes JE, Trute L, White D, Southey MC, Hammet F, Tesoriero A, Hutchins AM, Dite GS, et al. Distinct molecular pathogenesis of early-onset breast cancers in BRCA1 and BRCA2 mutation carriers: a population-based study. Cancer Research 1999; 59: 2011–2017.

1998

McCredie MRE, Dite GS, Giles GG and Hopper JL. Breast cancer in Australian women under the age of 40. Cancer Causes and Control 1998; 9: 189–198.

Southey MC, Batten LE, McCredie MRE, Giles GG, Dite GS, Hopper JL and Venter DJ. Estrogen receptor polymorphism at codon 325 and risk of breast cancer in women before age forty. Journal of the National Cancer Institute 1998; 90: 532–536.

Southey MC, Batten L, Andersen CR, McCredie MR, Giles GG, Dite G, et al. CFTR deltaF508 carrier status, early onset breast cancer risk and histological grading in a population-based sample. International Journal of Cancer 1998; 79: 487–489.

Armes JE, Egan AJM, Southey MC, Dite GS, McCredie MRE, Giles GG, et al. The histologic phenotypes of breast cancers occurring before age 40 in women with and without BRCA1 or BRCA2 germline mutations. Cancer 1998; 83: 2335–2345.

Dite GS, Bell RJ, Reddihough DS, Bessell C, Brennecke S and Sheedy M. Antenatal and perinatal antecedents of moderate and severe spastic cerebral palsy. Australian and New Zealand Journal of Obstetrics and Gynaecology 1998; 38: 1–7.